Protein Info for SO3207 in Shewanella oneidensis MR-1

Annotation: chemotaxis protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 758 PF01627: Hpt" amino acids 8 to 99 (92 residues), 62.1 bits, see alignment E=9.5e-21 PF02895: H-kinase_dim" amino acids 369 to 428 (60 residues), 56 bits, see alignment 8.7e-19 PF02518: HATPase_c" amino acids 476 to 615 (140 residues), 66.4 bits, see alignment E=6.2e-22 PF01584: CheW" amino acids 622 to 752 (131 residues), 88.6 bits, see alignment E=6.1e-29

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 100% identity to son:SO_3207)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ECD6 at UniProt or InterPro

Protein Sequence (758 amino acids)

>SO3207 chemotaxis protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTDLLNAIFRGFHTVKGGAGFLSL
TPMVDVCHEAENTFDLLRTGKRSVTAELMDIILQAVDAINTMFAQTQQGEQQDPADAALL
AKLKLLSSGEPLPSELGQRAPEPELIPEPEPVIETIVEVAVVEEMPVETVDSASSSIDEI
NDAEFEALLDALHGNGKGPGVATSNVAAASISNAVKPPAQAATSGDDITDDEFEALLDEL
HGSGKFSGKVEESVPAKLKAEVVAAPASATVPTATSVDSDEITDDEFERLLDELHGKGGT
PVKAVAKAEAAKTVPTPVAATATPVAPKASVTAAIPPTVKPKAEVVVAEKAPVKAAAAAS
STSVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTAD
LQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLVLVGEETDLDKNLVEALADPLVH
LVRNSVDHGIEMPNDREASGKPRTGVITLSASQEGDHILLKIEDDGAGMDPEKLKQIAIK
RGVLDEDSAARMTDNEAYNLIFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDS
MKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIV
RNKAVPLFYLEHWLHRNKTNFKHGDKKHGHVVIVQLGIMQIGFVVDALIGQEEVVIKPLG
ALLHGTPGMAGATITSDGGIALILDVPGLLKHYAKNKS