Protein Info for SO3126 in Shewanella oneidensis MR-1

Name: ogt
Annotation: methylated-DNA--protein-cysteine methyltransferase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 TIGR00589: methylated-DNA--[protein]-cysteine S-methyltransferase" amino acids 77 to 156 (80 residues), 120.5 bits, see alignment E=1.2e-39 PF01035: DNA_binding_1" amino acids 78 to 157 (80 residues), 111.4 bits, see alignment E=1.5e-36

Best Hits

Swiss-Prot: 46% identical to OGT_METBF: Methylated-DNA--protein-cysteine methyltransferase (ogt) from Methanosarcina barkeri (strain Fusaro / DSM 804)

KEGG orthology group: K00567, methylated-DNA-[protein]-cysteine S-methyltransferase [EC: 2.1.1.63] (inferred from 100% identity to son:SO_3126)

Predicted SEED Role

"Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)" in subsystem DNA repair, bacterial (EC 2.1.1.63)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.63

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ECL1 at UniProt or InterPro

Protein Sequence (167 amino acids)

>SO3126 methylated-DNA--protein-cysteine methyltransferase (NCBI ptt file) (Shewanella oneidensis MR-1)
MATLVTPVGELQLNANAYGLSHLTVMGSSRTEILLRHASEAEYALASEHIEQAKAQLARY
FNGDLTQFNLSLAPKGTEFQRQVWQALIAVDYGQCCSYADIAERIARPKAVRAVGAANGA
NPIAIIVPCHRIIGKNGQLTGYAYGLGMKQQLLMLESTSKGAHFTLE