Protein Info for SO3075 in Shewanella oneidensis MR-1

Annotation: RNA methyltransferase, TrmH family, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 140 to 159 (20 residues), see Phobius details PF00588: SpoU_methylase" amino acids 22 to 159 (138 residues), 75.8 bits, see alignment E=1.9e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_3075)

Predicted SEED Role

"tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34)" (EC 2.1.1.34)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ECQ8 at UniProt or InterPro

Protein Sequence (203 amino acids)

>SO3075 RNA methyltransferase, TrmH family, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MMSSSTTTLVDAVASPQAQQAVYIGLVNPKTPTNVGGIMRASGCYGVDAVFYTGKRYEYA
ARGPQQYNADTQSAAERIPLTGVTSLLDAIPAGTQLVCVDLVLGATPLPEFVHPERAFYV
FGPEDGTIGQEIIDRADAVVYVPTVGCMNLAASVNVLLYDRLAKTYRKQATNEAEFDGDA
LIRTSRDNNNRTRVKTTKRESSK