Protein Info for SO2885 in Shewanella oneidensis MR-1

Name: fadR
Annotation: fatty acid metabolism regulator protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 TIGR02812: fatty acid metabolism transcriptional regulator FadR" amino acids 2 to 235 (234 residues), 392.4 bits, see alignment E=3.7e-122 PF00392: GntR" amino acids 11 to 71 (61 residues), 67.5 bits, see alignment E=6.3e-23 PF07840: FadR_C" amino acids 72 to 234 (163 residues), 244.3 bits, see alignment E=5.8e-77

Best Hits

Swiss-Prot: 100% identical to FADR_SHEON: Fatty acid metabolism regulator protein (fadR) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K03603, GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA (inferred from 100% identity to son:SO_2885)

Predicted SEED Role

"Transcriptional regulator for fatty acid degradation FadR, GntR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ED80 at UniProt or InterPro

Protein Sequence (240 amino acids)

>SO2885 fatty acid metabolism regulator protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MIINAKGPASFAEKYIVRSIWENKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNN
PDTAMEVLAQIHQLEDTAESFAEYDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
SSSEARQLALNFYKELELLAKAKNYLDVPALMRTYGINSGKMWLQLRDDMPSSIAQQDSH