Protein Info for SO2883 in Shewanella oneidensis MR-1

Updated annotation (from data): yeaH component of nitrogen-related signalling system (of yeaGH-ycgB)
Rationale: PFam PF04285.8 (DUF444). conserved cofitness; yeaG is a protein kinase
Original annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 PF04285: DUF444" amino acids 4 to 420 (417 residues), 627.7 bits, see alignment E=5.5e-193

Best Hits

Swiss-Prot: 100% identical to Y2883_SHEON: UPF0229 protein SO_2883 (SO_2883) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K09786, hypothetical protein (inferred from 100% identity to son:SO_2883)

Predicted SEED Role

"UPF0229 protein YeaH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P59352 at UniProt or InterPro

Protein Sequence (422 amino acids)

>SO2883 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (Shewanella oneidensis MR-1)
MANFIDRRLNAKGKSTVNRQRFINRYKQQIKKAVSDAVTRRSVTDVDKGEKISIPTRDIS
EPMFHQGKGGVRDRVHPGNDQFTRGDKIDRPQGGSGGGAGKGDASDSGEGNDDFVFEISK
DEYLELLFEDLELPNLQKNRLNKLVEYQIYRAGFTNDGVPANINIVRSLRSSLARRIAMS
ASKKKLLKESEQELAELENIPGTKAELILDLKAQIEELKRKIAKVPFIDTFDLRFNNFSR
REVPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLTRTYKNLEVVYIRHHTQAKEV
DEHEFFYSQETGGTIVSSALKLMHEIQQARYPADEWNIYAAQASDGDNWADDSPTCKQLL
EQKILPLVRYFSYIEITNRAHQTLWREYESLQQHYDNIAVQHIRQAEDIYPVFRELFKKQ
AV