Protein Info for SO2850 in Shewanella oneidensis MR-1

Annotation: acetyltransferase, GNAT family (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 194 PF13302: Acetyltransf_3" amino acids 16 to 150 (135 residues), 67.7 bits, see alignment E=1.8e-22 PF00583: Acetyltransf_1" amino acids 41 to 148 (108 residues), 24.6 bits, see alignment E=2.6e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_2850)

Predicted SEED Role

"N-acetylglutamate synthase (EC 2.3.1.1)" in subsystem Arginine Biosynthesis extended (EC 2.3.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.1

Use Curated BLAST to search for 2.3.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EDB2 at UniProt or InterPro

Protein Sequence (194 amino acids)

>SO2850 acetyltransferase, GNAT family (NCBI ptt file) (Shewanella oneidensis MR-1)
MGNDDLSACLNGEYIVLEPLSLSHVAALTDGELWRLWFTSVPEPSEMKAYVMKALAGKSR
GECFPFAVRDKVSGEIVGCTRICHWESEHRHLEIGYTWYAKRAQRTGINTDAKLLLLTFA
FETLEAIAVEFRTHWHNQASRQAIARLGAKQDRVLRNNKILKDGTIRDTVVYSIIDSEWV
TVKQHLLFRLQQYP