Protein Info for SO2601 in Shewanella oneidensis MR-1

Annotation: carboxyl-terminal protease (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 682 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF17804: TSP_NTD" amino acids 53 to 233 (181 residues), 196.8 bits, see alignment E=8.4e-62 TIGR00225: C-terminal processing peptidase" amino acids 196 to 555 (360 residues), 359.8 bits, see alignment E=6.4e-112 PF00595: PDZ" amino acids 239 to 320 (82 residues), 36.6 bits, see alignment E=9.5e-13 PF03572: Peptidase_S41" amino acids 364 to 533 (170 residues), 160.9 bits, see alignment E=4.1e-51 PF11818: DUF3340" amino acids 539 to 671 (133 residues), 132.2 bits, see alignment E=3.6e-42

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to son:SO_2601)

Predicted SEED Role

"Tail-specific protease precursor (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EDY9 at UniProt or InterPro

Protein Sequence (682 amino acids)

>SO2601 carboxyl-terminal protease (NCBI ptt file) (Shewanella oneidensis MR-1)
MMRKLILATSIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRF
ALDDAFSAQIFDRYLQQLDYRRNVLTQADVDSFKPYINQFDDMLSSGELDPAYKMFDLVQ
KRRYEGFVYALSLLDKEMDFTAPGDVYDYDREDVAWPKDQAEINELWRQRVKYDALNLKL
TGKKWLEIVDILQKRYNNAIKRLTQTNSEDVFQAVMNAFSRSIEPHTSYLSPRNAERFQM
EMNLSLEGIGAQLQLEDDYTVIKSLIAGGPAAGSEKLSPEDKIVGVGQEGGEIVDVIGWR
LDDVVELIKGPKGSKVVLQILPKKGGSNAKPFNVTLVRDKIRLEDRAATSKIIEPKDGVY
ANRKVGVIQIPGFYMNLSQDVEKELLKLNEAKVEGVVIDLRGNGGGALTEAVLLTGLFID
MGPVVQVRDADGRVSAHRDNDGKTTYTGPLTVMVDRYSASASEIFAAALQDYDRALIVGE
SSFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIQKFYRINGGSTQLKGVTPNIAYPSALEP
GEYGEAEEKNALPWDKVPMAQYGTLNDITPELVASLEKKHLARIQNSVEFNYINQDIADF
KKHHKEKTVSLVESERIASREADEKKVLDRTNERRVANGLAPVKSMEDIKDDVVAPDAFL
DETAYITLDMVDAKKLANAGTK