Protein Info for SO2220 in Shewanella oneidensis MR-1

Annotation: MutT/nudix family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 PF00293: NUDIX" amino acids 29 to 141 (113 residues), 57 bits, see alignment E=1.1e-19

Best Hits

Swiss-Prot: 41% identical to NUDL_SALA4: Uncharacterized Nudix hydrolase NudL (nudL) from Salmonella agona (strain SL483)

KEGG orthology group: None (inferred from 100% identity to son:SO_2220)

Predicted SEED Role

"Hypothetical nudix hydrolase YeaB" in subsystem Nudix proteins (nucleoside triphosphate hydrolases)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EEY9 at UniProt or InterPro

Protein Sequence (195 amino acids)

>SO2220 MutT/nudix family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MDQTEFRLRFTLHPLAKQDPAALPHQGLRKAAVLIPLQEIDGELNLILTQRPMHLRAHPG
QISFPGGKIEASDPSAIMAALREAEEEIGLCRENVDVIGTFPAHNTFTGFEITPVVGIIK
QDFTLRLDPGEVADCFTVPLSFFIEPRHRHRKEFLRKGRYYSVHFIPYQQRFIWGATAAI
IDHLCRHVSLPEEIR