Protein Info for SO1861 in Shewanella oneidensis MR-1

Name: uvrC
Annotation: excinuclease ABC, C subunit (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 609 TIGR00194: excinuclease ABC subunit C" amino acids 9 to 588 (580 residues), 667.1 bits, see alignment E=1.2e-204 PF01541: GIY-YIG" amino acids 18 to 93 (76 residues), 41.5 bits, see alignment E=4e-14 PF02151: UVR" amino acids 203 to 237 (35 residues), 40.4 bits, see alignment (E = 5.4e-14) PF08459: UvrC_RNaseH_dom" amino acids 384 to 541 (158 residues), 170.4 bits, see alignment E=8.5e-54 PF14520: HHH_5" amino acids 556 to 608 (53 residues), 44.4 bits, see alignment 5.6e-15

Best Hits

Swiss-Prot: 100% identical to UVRC_SHEON: UvrABC system protein C (uvrC) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K03703, excinuclease ABC subunit C (inferred from 100% identity to son:SO_1861)

MetaCyc: 58% identical to UvrABC excision nuclease subunit C (Escherichia coli K-12 substr. MG1655)
3.1.25.-

Predicted SEED Role

"Excinuclease ABC subunit C" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EFV4 at UniProt or InterPro

Protein Sequence (609 amino acids)

>SO1861 excinuclease ABC, C subunit (NCBI ptt file) (Shewanella oneidensis MR-1)
MSTGFNAQSFLRTVTSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALV
SHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYILLSQHEHPRLAYHRG
PQREKGHYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVG
KVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAE
QQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLL
QFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLAITN
ATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGP
HKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVD
EKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTETSFSLEDDSPALHLIQHIRDESHRFA
ITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMA
QTIHDALRG