Protein Info for SO1755 in Shewanella oneidensis MR-1

Annotation: phosphoglucomutase/phosphomannomutase family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 45 to 184 (140 residues), 145.2 bits, E=2.1e-46
• PF02879: PGM_PMM_II
  • amino acids 219 to 317 (99 residues), 84 bits, E=2.1e-27
• PF02880: PGM_PMM_III
  • amino acids 326 to 443 (118 residues), 51.8 bits, E=1.8e-17
• PF00408: PGM_PMM_IV
  • amino acids 498 to 542 (45 residues), 29.6 bits, 1.2e-10

Best Hits

KEGG orthology group: K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 100% identity to son:SO_1755)

Predicted SEED Role

"Phosphomannomutase (EC 5.4.2.8) clustering with Aga operon" (EC 5.4.2.8)

MetaCyc Pathways

• GDP-mannose biosynthesis (2/4 steps found)
• β-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation (1/3 steps found)
• colanic acid building blocks biosynthesis (6/11 steps found)
• β-(1,4)-mannan degradation (1/7 steps found)
• superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis (4/14 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.8

Sequence Analysis Tools

See Q8EG54 at UniProt or InterPro

Protein Sequence (573 amino acids)

>SO1755 phosphoglucomutase/phosphomannomutase family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MNTHLQLQIQHWLKNDPDPSTQAQLQALIDSGNEAELAARFAGRLEFGTAGLRGVVGAGP
MGMNRLVIRQTSAGLGAYLLEQIHDVAERGVVIGYDGRHDSYTFAHDTASVLTAMGIKVR
LTAKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKVYWENGAQIIPPHDSGIAAKI
EQAATQAIPFMELDDAIKQGKLIWLNDDYYETYRRGVMHAKVLQNHTAPEKVSLAYTAMH
GVGADMAETVLKDAGFTQVYSVAAQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHSAML
ACANDPDADRFAVAVRKDDGEYQMLTGDQVGVLFGHYLLSHASADQRLVGTTIVSSSLLS
KIANGFGVESYTTLTGFKWLMNVGIAQSQPDNQFLFAYEEALGYTVGNMVWDKDGLSALV
AFAQLTAELAAKGQTIWDRLEQIYREQGFHLNAQASIALKPETPNIGAYLREHPPLTIGE
HAVVSTDDLKALSRRFADGKVENINLPASDVLTYRLSNGARVIVRPSGTEPKIKCYYEVV
EPMTAQDTLATAQARATQAMEAFISAHQASLPK