Protein Info for SO1623 in Shewanella oneidensis MR-1

Name: ptsG
Annotation: PTS system, glucose-specific IIBC component (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 transmembrane" amino acids 34 to 56 (23 residues), see Phobius details amino acids 65 to 89 (25 residues), see Phobius details amino acids 96 to 116 (21 residues), see Phobius details amino acids 135 to 152 (18 residues), see Phobius details amino acids 173 to 191 (19 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details amino acids 298 to 314 (17 residues), see Phobius details amino acids 320 to 343 (24 residues), see Phobius details amino acids 351 to 368 (18 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details PF02378: PTS_EIIC" amino acids 33 to 338 (306 residues), 182.3 bits, see alignment E=1.3e-57 TIGR00826: PTS system, glucose-like IIB component" amino acids 396 to 475 (80 residues), 57.2 bits, see alignment E=8.4e-20 PF00367: PTS_EIIB" amino acids 419 to 451 (33 residues), 48.3 bits, see alignment (E = 5.2e-17)

Best Hits

KEGG orthology group: K02778, PTS system, glucose-specific IIB component [EC: 2.7.1.69] K02779, PTS system, glucose-specific IIC component (inferred from 100% identity to son:SO_1623)

Predicted SEED Role

"PTS system, glucose-specific IIB component (EC 2.7.1.69) / PTS system, glucose-specific IIC component" in subsystem Trehalose Uptake and Utilization (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EGI1 at UniProt or InterPro

Protein Sequence (499 amino acids)

>SO1623 PTS system, glucose-specific IIBC component (NCBI ptt file) (Shewanella oneidensis MR-1)
MAGKLESTRQIRARRLGHFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMP
EVLNVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYQ
LPTQLVLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAM
GLGYVLAHIWPSLSLLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEV
GQYQLQDAEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAIWRCADNSERNRVAG
IMLSAAAASWLTGVTEPIEFAFMFVAPLLFLIHVMLSGLAYFVCIMLDIHHSIVFSHGLV
DFTLLFSLSRNTGWFAVLGPLTAVIYYILFRGSILAFNLKTPGRLQSDGTKGSKESLRAI
IAALGGRDNIVELNACLTRLRLSVHSPELVNKVRLSQLGAKGVIVMGKGVQIVYGTKAET
LRKVLQRYLDTRRYEVNCR