Protein Info for SO1606 in Shewanella oneidensis MR-1

Annotation: metallo-beta-lactamase superfamily protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 663 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00753: Lactamase_B" amino acids 125 to 210 (86 residues), 42.6 bits, see alignment E=1e-14 PF14863: Alkyl_sulf_dimr" amino acids 388 to 526 (139 residues), 187.6 bits, see alignment E=2.1e-59 PF14864: Alkyl_sulf_C" amino acids 534 to 657 (124 residues), 103.1 bits, see alignment E=2e-33

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_1606)

Predicted SEED Role

"Alkyl sulfatase (EC 3.1.6.-)" (EC 3.1.6.-)

Isozymes

Compare fitness of predicted isozymes for: 3.1.6.-

Use Curated BLAST to search for 3.1.6.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EGJ6 at UniProt or InterPro

Protein Sequence (663 amino acids)

>SO1606 metallo-beta-lactamase superfamily protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MQKSLMTISIIASFSLSAVAAEHEHEHISLHYQGKPATKQTIEVNKATAATLNFADKKAF
EEFSKNLIAELDEPTAAILRADFSFIGDKTPDTVNPSLYRQAQLNMVSNGLYKVTDGIYQ
VRGTDLANLTLIRGKTGWILYDVLLTKEAAKLSLEFALKHLPEGNNLPVVAMIYSHSHGD
HFGGSRAIKDMFPNVKVYGSNNITKEIVDENVLAGNAMSRRAAYQYGATLERNEQGIVDA
ALAKGLSKGEVTYVKPDVTLNAKDKWETLTIDGIDMVFMDASGTEAASEMATYIPSMKAL
WTAELTYHGMHNIYTLRGAKVRDAIKWSKDINELLNHFGNDAQVIFTAHSAPVFGNADVN
AYLRMQRDNYGLVHNQTLRLANNGVGIQDIGDAIQTTIPKTVRDTWYTNGYHGTYSHNAK
AVYNMYLGYFDMNPANLNPLPTKDESAKFVEYMGGAKAVLKHAKADYAQGEYRFVATALN
KVVMAEPNNTEARQLLADTYEQLGYQAEGAGWRNIYLTGAQELRAGIQPGAPKSASADIL
GEMDISTLFDFLAVRVDSIKAAELGLLRLNVITPDTKETLYVELSNGNLSNIQVDKPMEA
DTNLYIDKRYITGILLGKTTLKDLLANGSAKLEGDKTAFGKIMSTLVQFDANFEIVPLPP
TAK