Protein Info for SO1570 in Shewanella oneidensis MR-1

Annotation: GGDEF domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 170 to 193 (24 residues), see Phobius details amino acids 200 to 220 (21 residues), see Phobius details amino acids 232 to 252 (21 residues), see Phobius details amino acids 264 to 282 (19 residues), see Phobius details amino acids 288 to 309 (22 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 350 to 369 (20 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 42 to 121 (80 residues), 22.1 bits, see alignment E=1.9e-08 PF07695: 7TMR-DISM_7TM" amino acids 174 to 369 (196 residues), 103.5 bits, see alignment E=2.3e-33 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 392 to 542 (151 residues), 82 bits, see alignment E=2e-27 PF00990: GGDEF" amino acids 393 to 541 (149 residues), 90.3 bits, see alignment E=1.7e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_1570)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EGN0 at UniProt or InterPro

Protein Sequence (555 amino acids)

>SO1570 GGDEF domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSKTNLHNFWCFLLLFWTFSPFALSAEIALDSPYLFHAEAKQLPPADFKEVSQWMGQLKE
ASSVSLTGGDYWMVSPVMVNSRQTRWVVDASNSIIESVDYWLLGSDGSVQFAHSGYYAPY
EFLFDYGRKVRLNMGTDYWLVTRLSSQYFSSAPEVALESQEAHQLTTDRMAMAILLCLGG
LLFIAFYNLLIYISIFDKAFLYYGLYVLAYLGGWALTFHLPAHLFNFHQLELHHLFFISL
PIFNIMFYKHFLQLPSYSPRLWRLSQYLLIACVIALPTSIWLLPYTAIIASVLIMLWIAL
AITCGNVCLMKGFAPARYFIMAFTCLLLPAVIILPGNMGITPDFIEHAEFATLLGGTVDA
LLLSLALANKLKLMSEERKAHIEELGIAWEKARLDALTRVGNRYAFDEFMNSQLAFANKV
VNPMALVLLNADSLKMVNDTLGHQEGDRLLQRLVQFLQSTNIAQLKIYRISGDEFVAILP
ASGVTSFVNTLRGLTAQFATEGFRDCQFSFGIAINADVANPHEWLRSADTSLYHSRMEKR
RQEYADTRTGEIVSL