Protein Info for SO1427 in Shewanella oneidensis MR-1

Annotation: decaheme cytochrome c (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF13435: Cytochrome_C554" amino acids 48 to 97 (50 residues), 18.1 bits, see alignment 1.5e-06 TIGR03508: decaheme c-type cytochrome, DmsE family" amino acids 55 to 312 (258 residues), 345.6 bits, see alignment E=1.8e-107 PF22678: Cytochrom_c_NrfB-like" amino acids 92 to 168 (77 residues), 48.5 bits, see alignment E=3.6e-16 PF09699: Paired_CXXCH_1" amino acids 148 to 183 (36 residues), 28.7 bits, see alignment 2.9e-10 amino acids 193 to 233 (41 residues), 44.1 bits, see alignment 4.8e-15 amino acids 240 to 277 (38 residues), 51.4 bits, see alignment 2.4e-17 TIGR01905: doubled CXXCH domain" amino acids 151 to 182 (32 residues), 26.4 bits, see alignment 5.1e-10 amino acids 199 to 232 (34 residues), 32.2 bits, see alignment 8e-12 amino acids 240 to 277 (38 residues), 43 bits, see alignment 3.3e-15

Best Hits

Swiss-Prot: 68% identical to MTRA_SHEB8: Multiheme cytochrome MtrA (mtrA) from Shewanella baltica (strain OS185)

KEGG orthology group: None (inferred from 100% identity to son:SO_1427)

Predicted SEED Role

"Decaheme cytochrome c MtrA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EH05 at UniProt or InterPro

Protein Sequence (318 amino acids)

>SO1427 decaheme cytochrome c (NCBI ptt file) (Shewanella oneidensis MR-1)
MRWRKIKTLIMGASLFLILSPSVKAQEIPSTHETGEQIEKILTDKFAEGKYSTKGADSCL
MCHRKNNTVMAIFDGVHGDINNSKSPMAGLQCEACHGPLGQHNKGGKEPMISFGSDSPLS
APSQNTVCLGCHQKTEQSGWHSSLHNMEEIACADCHKVHAAKDPVLQKQQVSQVCTSCHT
RQKSDMNKRSSHPLKWNDMTCIDCHNPHGSFNESALKKTSVNDTCYSCHAEKRGPFLWEH
APVTENCSTCHNPHGSVNDALVKQRVPQLCQQCHADDGHASRVVTPPGADAFGAGMGCLN
CHSQIHGSNHPSGSNFAR