Protein Info for SO1245 in Shewanella oneidensis MR-1

Annotation: membrane protein, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 97 to 117 (21 residues), see Phobius details amino acids 136 to 161 (26 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details amino acids 240 to 258 (19 residues), see Phobius details amino acids 319 to 340 (22 residues), see Phobius details amino acids 346 to 363 (18 residues), see Phobius details amino acids 372 to 390 (19 residues), see Phobius details amino acids 396 to 418 (23 residues), see Phobius details amino acids 427 to 451 (25 residues), see Phobius details PF07670: Gate" amino acids 137 to 234 (98 residues), 54.8 bits, see alignment E=5.8e-19

Best Hits

Swiss-Prot: 50% identical to Y2044_BACPE: Uncharacterized protein BpOF4_10220 (BpOF4_10220) from Bacillus pseudofirmus (strain OF4)

KEGG orthology group: None (inferred from 100% identity to son:SO_1245)

Predicted SEED Role

"Predicted arginine uptake transporter" in subsystem Arginine Biosynthesis extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EHH6 at UniProt or InterPro

Protein Sequence (452 amino acids)

>SO1245 membrane protein, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MATEHKNRNIKTILTFIVPSLIGLLLFVTPISYNDAITIPIAIISKALQSVLSDVLTLIV
TVIVVSMALASVLTKLLKPKFVLNNHFLNGLLNISPMWLITRVVGAIFIVLTYFAIGPAV
INSSSTGALVLNDLLPVLFSVFIFAGMLLPLLLNFGLLELFGTLMTKVMRPVFNLPGRSA
IDCMASWLGDGSVGILLTSKQYEARFYTQREAAVIGTTFSAVSITFCLVVISQVKLEPMF
VPFYLTVCLAGFAAAVIVPKLPPLSWKKDNYIDDTPRQPDDEMIPAGYGAFSWGFDKALE
KAASAGGVKAVLHEGIKNVIDMVFGIIPVVMAIGTTALIIAEHTPIFNYLGMPFIPLLEL
LHIPEATEASKTIVVGFADMFIPSILASSIESDMTRFVIAALSVTQLIYMSEVGALLIGS
KIPVNFVELFVVFILRTLVTLPVIAGVAHLLF