Protein Info for SO1226 in Shewanella oneidensis MR-1

Name: radA
Annotation: DNA repair protein RadA (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 TIGR00416: DNA repair protein RadA" amino acids 1 to 451 (451 residues), 708.3 bits, see alignment E=2e-217 PF18073: Rubredoxin_2" amino acids 8 to 35 (28 residues), 41.6 bits, see alignment (E = 2.8e-14) PF06745: ATPase" amino acids 80 to 149 (70 residues), 38.4 bits, see alignment E=3.3e-13 PF13481: AAA_25" amino acids 84 to 222 (139 residues), 59.1 bits, see alignment E=1.7e-19 PF13541: ChlI" amino acids 345 to 430 (86 residues), 33.3 bits, see alignment E=1.4e-11 PF05362: Lon_C" amino acids 352 to 448 (97 residues), 29.7 bits, see alignment E=1.6e-10

Best Hits

Swiss-Prot: 78% identical to RADA_SALTY: DNA repair protein RadA (radA) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K04485, DNA repair protein RadA/Sms (inferred from 100% identity to son:SO_1226)

Predicted SEED Role

"DNA repair protein RadA" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EHJ5 at UniProt or InterPro

Protein Sequence (454 amino acids)

>SO1226 DNA repair protein RadA (NCBI ptt file) (Shewanella oneidensis MR-1)
MAKNKTAYVCNECGQDFPRWQGQCSACHEWNTITEVRLGAASPGRGTKFAGYAGAGSSEV
KTLDQIDLNALPRIVSHFGELDRVLGGGIVPGSAILIGGHPGAGKSTLLLQTLCHLAEQM
PALYVTGEESLQQVAMRAHRLGLPTNKLRMLSETSVEQICEIALQESPKVIVVDSIQVMH
MSDVASSPGSVSQVRESASYLTRFAKQHGIAVIMVGHVTKDGSLAGPKVLEHCIDCSVMF
EGDSDSRYRTLRSHKNRFGAINELGVFAMTERGLKEVANPSAIFLSRGEEESSGSLVMVV
WEGTRPLLVELQVLVDNSAMSNPRRVAVGMDANRLAMLLAVMHRHGGLQMSDQDVFVNVV
GGVKVTETSADLTLLLAMVSSFRGDILPSDLVVFGEVGLSGEIRPVPNGQERLVEAAKHG
FKRAIVPRANVPKKPPVGMEVVGVSKLSEALEAI