Protein Info for SO1180 in Shewanella oneidensis MR-1

Annotation: PhoH family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 355 PF02562: PhoH" amino acids 110 to 313 (204 residues), 328 bits, see alignment E=3e-102 PF13604: AAA_30" amino acids 114 to 266 (153 residues), 30.8 bits, see alignment E=3.5e-11 PF13245: AAA_19" amino acids 120 to 266 (147 residues), 27.2 bits, see alignment E=5.9e-10

Best Hits

Swiss-Prot: 74% identical to PHOL_ECOLI: PhoH-like protein (ybeZ) from Escherichia coli (strain K12)

KEGG orthology group: K06217, phosphate starvation-inducible protein PhoH and related proteins (inferred from 100% identity to son:SO_1180)

Predicted SEED Role

"Phosphate starvation-inducible protein PhoH, predicted ATPase" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EHN8 at UniProt or InterPro

Protein Sequence (355 amino acids)

>SO1180 PhoH family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MNLYLEPAETRRLASLCGPFDDNIKQIERRVGVEIVRKNNHFQITGLPRHCLSANNLLKQ
LYIETQTVKGSTPDLDPEQVHLAIQEAIALEQDDSGDDKALFIKTRRGVIKPRNPNQSTY
VANITRHDITFGIGPAGTGKTYLAVAAAVDALERQEVRRILLTRPAVEAGEKLGFLPGDL
SQKVDPYLRPLYDALFEMLGFEKVERLIEKNVIEVAPLAYMRGRTLNDAFIILDESQNTT
VEQMKMFLTRIGFNSRAVITGDITQTDLPKHIKSGLRHAIEVLSQVEEISFNFFVSQDVV
RHPVVARIVEAYEAFDRKEQALKAEKERRDYQHNASQPSSQLQPQIQQEVLKHES