Protein Info for SO1066 in Shewanella oneidensis MR-1

Annotation: extracellular nuclease (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 871 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 849 to 865 (17 residues), see Phobius details PF00932: LTD" amino acids 21 to 128 (108 residues), 66.1 bits, see alignment E=3.6e-22 PF03372: Exo_endo_phos" amino acids 467 to 823 (357 residues), 25.3 bits, see alignment E=1.3e-09 TIGR03501: GlyGly-CTERM domain" amino acids 849 to 869 (21 residues), 17.1 bits, see alignment (E = 3.7e-07)

Best Hits

KEGG orthology group: K07004, (no description) (inferred from 100% identity to son:SO_1066)

Predicted SEED Role

"Extracellular and/or outer membrane deoxyribonuclease NucH/SO1066"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EHY8 at UniProt or InterPro

Protein Sequence (871 amino acids)

>SO1066 extracellular nuclease (NCBI ptt file) (Shewanella oneidensis MR-1)
MENVNKLTAVSLAVAAALPMMANANVMITEYVEGSSNNKAIELYNSGNTAIDLTGYKLVR
YKDGATDAADMQVLDGQSIAPKATKVILNSSGVITLPQGVDSFSGTLSFNGGDAVALVKD
GAVVDIIGDVPTPVGWGLDVTLKRKLDSLVANTVFNPAQWEQLPKDTFTGLGSLDTPTKP
ETPAFSCSGAKIVPIYQVQGAGESSPYVPAGAFESESEVTVRGVVTARGENLFKGFYLQE
VKGDNSPYTSDGVFVFLGEAPPPAIQPGVEICVQGKVKEYFGLTQIDIKTDKKFEAGTKG
EVPVAAPFYVAEGETLAQALERFEGMNVLLDAGSDLKINRTFSYDYAGKRNNMLVSYKAP
LMKPTQLYPALSAEATALAKSNRENQLFIESDYKPADGIIPYFPDFNAETGYIRVGDQLT
NLQGVVGYSYGAYRLVATNTITAGDFIRGDDRTDAPSVATKGDIRVASFNVLNFFNDVVG
GDTNPSGGNRGALTEEEMLLQRTKIVSAITAMNADIVGLMEIANNGFGEKSAIKNLVDAL
NEKQTTENAYSYIQIADTDKYDGKYFGSDAITVGMLYRAGKVSLAGAARTIETPEQHASV
GSVTRIKDGKTETNPGNDAYQRHSLAQTFKIHDQNLTVVVNHLKSKNSGCLEDWVNFEES
VDPADLQGRCNEFRVSAAKVLGEALKDVKGDLLVIGDMNAYGMEDPLRVLTDFDASKSDR
DIMTASWTTLNGKVYERQGSKIDKGYGLINLNTKAHGTGTYSYSYNGELGNLDHALANTS
LAKRLVDIEDWHINSVESSLFEFGKKFSGNLVKSENAFSASDHDPVIVALSYPAPVVPPK
PQPTPKDDGGALGYLGLALLSLLGLQRRRRY