Protein Info for SO0876 in Shewanella oneidensis MR-1

Name: pepB
Annotation: peptidase B (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 PF12404: DUF3663" amino acids 10 to 85 (76 residues), 100.8 bits, see alignment E=3.5e-33 PF00883: Peptidase_M17" amino acids 112 to 424 (313 residues), 319 bits, see alignment E=3.4e-99

Best Hits

Swiss-Prot: 52% identical to PEPB_VIBPA: Peptidase B (pepB) from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

KEGG orthology group: K07751, PepB aminopeptidase [EC: 3.4.11.23] (inferred from 100% identity to son:SO_0876)

Predicted SEED Role

"Peptidase B (EC 3.4.11.23)" (EC 3.4.11.23)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EIG3 at UniProt or InterPro

Protein Sequence (430 amino acids)

>SO0876 peptidase B (NCBI ptt file) (Shewanella oneidensis MR-1)
MSELKVTEVMSVALTKDTPAAHWGKADVTFAAEGALVHLSGGDELRQIQMAARKLRNQGI
SNVALSGSLWDLNSQWVFAQGFATAKPGYKIQWCGDAEVQAELQRRIEVATFARQLINET
PENLSPVKLAQQAAKWLADIGGAKVSYRIIEGEALLAEQWIGIHAVGRGSERPPAMLELD
FNPLAADAPVSVALVGKGITFDSGGYSIKASEGMLGMKCDMGGAATVTAALGLAIKSGLN
KRVKLFLCCAENLISGRAYKLGDILTYKNGVTVEVVNTDAEGRLVLADGLQAASATGAPF
IIDAATLTGAAVMAVGSNYNAIFSPQVDVLQLAQQKASTVAERVWPLPLDPWHKEMCPSS
YADTANSRPVKGGGAGGASNAAGFLWRFVSPEAKWLHVDLAAAFEDSASALWGAGATTHG
VLTISELIKG