Protein Info for SO0719 in Shewanella oneidensis MR-1

Annotation: TonB-dependent receptor, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 747 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01785: TonB-dependent heme/hemoglobin receptor family protein" amino acids 31 to 747 (717 residues), 358.6 bits, see alignment E=7e-111 TIGR01786: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein" amino acids 35 to 747 (713 residues), 342.1 bits, see alignment E=7.1e-106 PF07715: Plug" amino acids 45 to 155 (111 residues), 70.4 bits, see alignment E=1.7e-23 PF00593: TonB_dep_Rec_b-barrel" amino acids 261 to 702 (442 residues), 180.9 bits, see alignment E=8.2e-57

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to son:SO_0719)

Predicted SEED Role

"TonB-dependent heme receptor HutR" in subsystem Iron acquisition in Vibrio

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EIW0 at UniProt or InterPro

Protein Sequence (747 amino acids)

>SO0719 TonB-dependent receptor, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MKPLPLSLCALAVASALPVWAEEQAKPLINEVIVVSGSRMEQNIEQVAGSILVIDEEAIE
RNMSNDFGSLFRNESAVDIKGGAGKPTSVTIRGIGGNRVMMVKDGVRVNNQYASPLGPGA
EGTGRGLTEVQSLKQIEVVKAAASTMYGSDALGGVVVMRTKDASDYLRGEDYYVSLNAGY
SGINNEYSGGFTSAAAYSDFENLLTYQHRKGEELPNYFDTQPESDLLQDSLLFKSKYRFN
EHTTVQLTLDYLEQTLERWEDKLNRAQVPQERIDTDRDTQVINGALQLRSDKATYLHDDL
TVTAYFGQTEQLEHRDYFDLRTAARPLTEYRDYEFKDQRLGLTSTFSKYIGAEGYGHQLT
YGMDYEWSQMMRHRNNNIASNGGDWQTETPFTFADTDSNRLGLFLQDDITLLNGDLNLIG
GLRYDYFRNSPDQQQAMEAGKDPADFAVMSDTFWSPKVGLVYKLTDTVSAYAQYAYGYKM
PTPDQKWGELEVDGGSMTDVIIQANYDLKSEQSHTWELGIRGNHADTQYELTTFDTHAVD
FSDWQYVSFKPPVFGPVMQPMEFKYQYFNRDQVTLYGAEAQANHWLTDSIELWGNISYTH
GTDENGQNLNSVSPLKGNLGVNWYSDIGGMETDIGAVVRWADKMDRTNDINLTIDDICVM
GQCIPKESFNEVYNTAGYAVLDLTMGLHVTDNLHLRAGVYNLFDKEYVDYADVAGQSVFL
LNSTMNLQKDDFTQPGRYFNLSMNYQF