Protein Info for SO0706 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 TIGR03071: HipA N-terminal domain" amino acids 9 to 105 (97 residues), 51.7 bits, see alignment E=3.8e-18 PF13657: Couple_hipA" amino acids 9 to 105 (97 residues), 69.5 bits, see alignment E=2.9e-23 PF07804: HipA_C" amino acids 146 to 388 (243 residues), 166.1 bits, see alignment E=9.5e-53

Best Hits

Swiss-Prot: 100% identical to HIPA_SHEON: Serine/threonine-protein kinase toxin HipA (hipA) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K07154, (no description) (inferred from 100% identity to son:SO_0706)

Predicted SEED Role

"HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EIX3 at UniProt or InterPro

Protein Sequence (433 amino acids)

>SO0706 conserved hypothetical protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSTAKTLTLEMHLGDLMIGELSFDATADTFAVHYTKDWQQSGFPLSPTIPLDGTGTSNQI
SMFLVNLLPENKGLDYLIESLGVSKGNTFALIRAIGLDTAGAIAFVPKGALLPETQLRPI
KAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYNGKEFAFAEGTLSSTHIVKFE
KYHHLVINEFITMRLAKVLGMNVANVDIVHFGRYKALCVERFDRRNIPGEQRVLRRHIVD
SCQALGFSVSKKYERNFGTGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNL
LTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQQLAMAIDDEFDPNSIYAYQL
AAFMDGLGLPRNLLISNLTRIARRIPQAIAEVILMLPPLDEDEASFVAHYKTQLLARCER
YLGFVDEVRDVEV