Protein Info for SO0695 in Shewanella oneidensis MR-1

Annotation: glutathione-regulated potassium-efflux system protein KefC, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 78 to 102 (25 residues), see Phobius details amino acids 113 to 132 (20 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 170 to 187 (18 residues), see Phobius details amino acids 199 to 215 (17 residues), see Phobius details amino acids 221 to 237 (17 residues), see Phobius details amino acids 248 to 267 (20 residues), see Phobius details amino acids 273 to 294 (22 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 335 to 360 (26 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 7 to 351 (345 residues), 159 bits, see alignment E=1.6e-50 PF02254: TrkA_N" amino acids 390 to 506 (117 residues), 70 bits, see alignment E=2.3e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_0695)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system protein KefB" in subsystem Glutathione-regulated potassium-efflux system and associated functions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EIY2 at UniProt or InterPro

Protein Sequence (547 amino acids)

>SO0695 glutathione-regulated potassium-efflux system protein KefC, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MEPAILIITLICGMLVSRIGLPPLIGYLVAGFVLFVMGIEKESMPLLQELANLGVTLLLF
AIGLKLDIRSLFKAEVWAGSSVHLILSILVFVPILKILGLLGLSQLTSLGIEQLTLLAFA
LSFSSTVFAVKVLEDKGDMQSLYGRVAIGILIMQDIFAVLFLTISKGDVPSVWAFALLLL
PLAKPLIYKAFDRVGHGELLVLFGLVMALVVGAWLFESLGLKPDLGALVIGILLAGHKKA
SELAKSLFYFKELFLVAFFLTIGLNGLPTVSDIVLAALLVLLVPLKILLFVYILTRFKLR
SRTSMLGSFNLGNFSEFGLIVAAVATSKGWLPSHWLVIIAVALSFSFLLAAPLNATVGSI
YQRFQLRLVRLEKRPLHPEDRPIAIGNPRFLILGMGRIGSGAYDELRARFDGEILGIEHK
QDLVDLHRAKGRNVVQGDASDTDFWEKLDKAPNLELVLLAMPHHAGNLFAVEQLNKLNYQ
GKISAIVQYGEDAASLRNSGVHSVYNLYEAAGAGFVDHVVHELLPDSETKAGTEAQEGTQ
KQTSSLV