Protein Info for SO0569 in Shewanella oneidensis MR-1

Annotation: sensory box/GGDEF family protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 324 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 152 to 315 (164 residues), 187.8 bits, see alignment E=6.3e-60 PF00990: GGDEF" amino acids 157 to 312 (156 residues), 153.5 bits, see alignment E=2.1e-49

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_0569)

Predicted SEED Role

"diguanylate cyclase (GGDEF domain) with PAS/PAC sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EJ99 at UniProt or InterPro

Protein Sequence (324 amino acids)

>SO0569 sensory box/GGDEF family protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSNDQSAMNELHWLIDMVQTIEVGLVVLDRDYNIQLWNGFMENHSGVSPNSIKGQNLFSR
FPDLPATWLKQKMESVFMLKNRAFISWEQRPYVFQFKNYRPITGRADFMYQNVTLLPLAS
LTGKITHISVIVYDVTDIAVNKLQLKAANEQLERLSQTDGLTQLHNRRHWQQCLEHEYDL
YARYSGIASLVMIDIDHFKNINDTYGHLAGDKVIQHIAHILSHSLRETDCAGRYGGEEFA
VVMPSTCGADALNFTERLREKIASSTVVYEGLKIKVTVSLGVCELGKHISSSSSWISCSD
KALYEAKQKGRNCTVLHCAPTSAE