Protein Info for SO0549 in Shewanella oneidensis MR-1

Annotation: chemotaxis protein CheY/response regulator receiver domain protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 PF00072: Response_reg" amino acids 14 to 125 (112 residues), 43.5 bits, see alignment E=1.7e-15 amino acids 149 to 259 (111 residues), 83.8 bits, see alignment E=5e-28

Best Hits

KEGG orthology group: K03413, two-component system, chemotaxis family, response regulator CheY (inferred from 100% identity to son:SO_0549)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EJB8 at UniProt or InterPro

Protein Sequence (267 amino acids)

>SO0549 chemotaxis protein CheY/response regulator receiver domain protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MTMTHLSPSELSMLIVEPSETQRRIIIKCLQQEGIVSIEHAANIAEAKGLIARHKPDLIA
SAMHFEDGTATEFLSYLRSKSEYKDIQFMLVSSECRREQLESFRQSGVVAILPKPFNAEH
LGKALNATIDLLSHDELDLSHFDVHDVRVLVVDDSRMARNVIKRTIGNLGIKLITEAEDG
AQAIELMRHNMFDLIITDYNMPSVDGLALTQFIRSESQQSHVPILMVSSEANDAHLSNVS
QAGVNALCDKPFEPKLVKQLLYQLLEE