Protein Info for SO0519 in Shewanella oneidensis MR-1

Annotation: cation efflux protein, putative (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 signal peptide" amino acids 1 to 50 (50 residues), see Phobius details PF16576: HlyD_D23" amino acids 109 to 331 (223 residues), 116.9 bits, see alignment E=8.3e-38 PF13437: HlyD_3" amino acids 231 to 322 (92 residues), 54.9 bits, see alignment E=1.3e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_0519)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EJE8 at UniProt or InterPro

Protein Sequence (433 amino acids)

>SO0519 cation efflux protein, putative (NCBI ptt file) (Shewanella oneidensis MR-1)
MNSTTQKSFFHSLGNVSATGFTSVFTPSRLALALMLTSLILIVPTPTFAGEGHDHAAEKQ
VNNTAKNTAVEQAQDDHSEQALTFTPAQLELAGIRLLPLSSDSLSLTNLNLDVRATATLV
VDRDKTATLAPQLDVRVQARHVVPGQEVKKGEPLLTLGGAEVAKAQAEYINAAAEWSRVR
RMSEGAVSVSRRMQAQVDAELKRAILEAIKMTSEQIRTLESKPEAIGSYQLLAPIDGRVQ
QDIAMLGQVFSAGTPLMQLTDESHLWVEAQLTPAQAVNVKVGAPALIQVGDNTLAGKIIG
RSHELDSVTRTEQVLVSMPNPDHILHAGQFAELYFADASQNIAVASGSGASSGIVLPDAA
LTRSGDGDWQIFIQDEDGFEAIEVELVQRQRGLSLVRGSELDKARQAQLKVVVEGAFFLA
SEQAKAGFDIHAH