Protein Info for SO0365 in Shewanella oneidensis MR-1

Annotation: hypothetical permeases of the major facilitator superfamily (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 transmembrane" amino acids 47 to 71 (25 residues), see Phobius details amino acids 91 to 111 (21 residues), see Phobius details amino acids 117 to 135 (19 residues), see Phobius details amino acids 160 to 180 (21 residues), see Phobius details amino acids 186 to 210 (25 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 273 to 295 (23 residues), see Phobius details amino acids 306 to 325 (20 residues), see Phobius details amino acids 331 to 355 (25 residues), see Phobius details amino acids 367 to 390 (24 residues), see Phobius details amino acids 409 to 429 (21 residues), see Phobius details PF07690: MFS_1" amino acids 43 to 263 (221 residues), 42.1 bits, see alignment E=5.6e-15 amino acids 251 to 443 (193 residues), 46 bits, see alignment E=3.5e-16 PF12832: MFS_1_like" amino acids 52 to 393 (342 residues), 30.7 bits, see alignment E=1.7e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to son:SO_0365)

Predicted SEED Role

"Major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EJU2 at UniProt or InterPro

Protein Sequence (474 amino acids)

>SO0365 hypothetical permeases of the major facilitator superfamily (NCBI ptt file) (Shewanella oneidensis MR-1)
MGSHVAPTALTCARRSARNLWLRCTLRRSQQEAVASSMMTATSDNFFNAYAIFLGASLAQ
MGFVTGLPQLFGALSQLVSVWLASHFSRRGFIVCCATLQAVVVLAMGALAAFRPDHAVWI
FIALAVGYHGFINLIQPHWRAWMGSIVPERRRGTFFAARTRLTMGASLSVFFIGGGILTF
TDSLQMAWLGFTLLFSIAAMGRFVSAWLLLQMHDPEPRAAKQRGVFIQTIRNFRGAWKDK
TFRQYSLFVASMQAMVAISAPFFAVYMLEDLHFSYIEFVLASVASIATQFVTLKFWGRFS
DQFGNRLVMIITSCMIPSLPLLWLFSDNYLYILLIQAFSGLAWSGFTLSTANYLYDIRPF
RSDFATYAALQASLSAGFVFVGAMVGGTIASHAADFLVWSGWNTWLSSPIFVVFLVSTIL
RAFVTLWFIPRSVEPKVRPRPQLLQLIFRIRGFNAISGVSLDWLTVVKRRKNND