Protein Info for SO0285 in Shewanella oneidensis MR-1

Annotation: type IV pilus biogenesis protein PilQ (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 signal peptide" amino acids 7 to 11 (5 residues), see Phobius details amino acids 32 to 33 (2 residues), see Phobius details transmembrane" amino acids 12 to 31 (20 residues), see Phobius details PF11741: AMIN" amino acids 158 to 248 (91 residues), 33.4 bits, see alignment E=7.9e-12 TIGR02515: type IV pilus secretin PilQ" amino acids 271 to 681 (411 residues), 517.8 bits, see alignment E=1.2e-159 PF07660: STN" amino acids 299 to 343 (45 residues), 30.4 bits, see alignment 5.4e-11 PF03958: Secretin_N" amino acids 371 to 434 (64 residues), 60.7 bits, see alignment E=2.6e-20 PF00263: Secretin" amino acids 522 to 680 (159 residues), 166.6 bits, see alignment E=7.9e-53

Best Hits

KEGG orthology group: K02666, type IV pilus assembly protein PilQ (inferred from 100% identity to son:SO_0285)

Predicted SEED Role

"Type IV pilus biogenesis protein PilQ" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EK21 at UniProt or InterPro

Protein Sequence (684 amino acids)

>SO0285 type IV pilus biogenesis protein PilQ (NCBI ptt file) (Shewanella oneidensis MR-1)
MKSSAAIKIPLSFLTSGLVKSVIGIALLFGFLPSSFAENRLIDVKYHALVDHQLAVELVF
EDAISAPKIDSNASPAELVLTFDNSISGLSKDRLPINQVGVKDIVTSQHDARLKVTLGLS
KVKPYQGSVVGNSYRLTINDGVASSQASNNPFVNSVKNIDFRRNSNGGGDLLVYLNNRSV
AANVEQIGAKLEVQLYNTDINNDLLYVMDVQDFSTPVKNFETFKDDLTARILVDVTGNYE
FNFKQEDNLFILSINKVERVVATKDIKKYNGKTLSLNFQNISVRTVLQIIADYNNFNLVT
SDSVEGDITLRLDDVPWDQALDLILQTKGLDKRIEGNILMVAPSEELAIRESQNLKNKQE
VKELAPLYSEYLQINYAKATDIAELLKGADSSLLSPRGSVAVDERTNTVLVKDTAEIIEN
IHRLVEVLDIPIRQVLIESRMVTVKDDVSEDLGIRWGVTDQQGNKGTSGSLEGAGDIANG
KVPSLDNRLNVNLPAAVTNPTSIAFHVAKLADGTILDLELSALEQENKGEIIASPRITTS
NQKAAYIEQGVEIPYVQSTSSGATSVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGK
TVDTPTGPAVAIDTQRIGTQVLVDNGETIVLGGIYQQNLISRVSKVPILGDIPLVGFLFR
NTTDKNERQELLIFVTPKIVNEKL