Protein Info for SO0196 in Shewanella oneidensis MR-1

Name: selD
Annotation: selenide, water dikinase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 TIGR00476: selenide, water dikinase" amino acids 13 to 319 (307 residues), 456.2 bits, see alignment E=2.8e-141 PF00586: AIRS" amino acids 56 to 162 (107 residues), 85.9 bits, see alignment E=2.7e-28 PF02769: AIRS_C" amino acids 175 to 339 (165 residues), 71.4 bits, see alignment E=1e-23

Best Hits

Swiss-Prot: 100% identical to SELD_SHEON: Selenide, water dikinase (selD) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K01008, selenide, water dikinase [EC: 2.7.9.3] (inferred from 100% identity to son:SO_0196)

MetaCyc: 63% identical to selenide, water dikinase (Escherichia coli K-12 substr. MG1655)
Selenide, water dikinase. [EC: 2.7.9.3]

Predicted SEED Role

"Selenide,water dikinase (EC 2.7.9.3)" in subsystem Selenocysteine metabolism (EC 2.7.9.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.9.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EK99 at UniProt or InterPro

Protein Sequence (352 amino acids)

>SO0196 selenide, water dikinase (NCBI ptt file) (Shewanella oneidensis MR-1)
MSNSTLPSTDSIKLTEYSHGAGCGCKISPKVLTTILASQLPVFTDPNLLVGNQSRDDAAV
YKLNEEVGIISTTDFFMPIVDDPFTFGRIAATNAISDIYAMGGTPMMAIAILGWPINKLP
AEIAQQVVDGGRQACMEAGIMLAGGHSIDAPEPIFGLAVTGQIALTDLKQNDTAKAGDRL
YLTKPIGIGILTTAQKQKKLKDEDSHIAVNAMCQLNSIGAQIAKINGVNALTDVTGFGLA
GHLLEMCQGAKLTAKLKLDAVPLLPRALDYLAQGCVPGGTHRNYDSYGEHLPELTDHQKA
ILCDPQTSGGLLVAVSSEAEAELVALLNANQIEPICIGSLEAPTTATNVVLC