Protein Info for SO0138 in Shewanella oneidensis MR-1

Name: moeA
Annotation: molybdopterin biosynthesis MoeA protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 PF03453: MoeA_N" amino acids 16 to 177 (162 residues), 150.4 bits, see alignment E=5.3e-48 TIGR00177: molybdenum cofactor synthesis domain" amino acids 187 to 321 (135 residues), 108.6 bits, see alignment E=1.3e-35 PF00994: MoCF_biosynth" amino acids 192 to 326 (135 residues), 109.7 bits, see alignment E=1.5e-35 PF03454: MoeA_C" amino acids 341 to 412 (72 residues), 64 bits, see alignment E=1.8e-21

Best Hits

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA (inferred from 100% identity to son:SO_0138)

Predicted SEED Role

"Molybdopterin biosynthesis protein MoeA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EKF5 at UniProt or InterPro

Protein Sequence (417 amino acids)

>SO0138 molybdopterin biosynthesis MoeA protein (NCBI ptt file) (Shewanella oneidensis MR-1)
MSVKADPCSQPSLMHPDQAIPLMLEQVSPVSDTEVVSLPHALGRVLAEDLASCIDLPPFD
NSSMDGYAFRFADLTSEAKQTTLTLIGSSFAGHGFEGRITPNSCVRIMTGAPVPAGYDTV
QMQEETQANGDQIQINHPKAKGVNVRCQGEELLQGTKVLKAGIEINAAELGVLATIGVSQ
VRVYRQLKVAFFSTGDELRPVGSDLAPGQIYDSNRYSIQGLLSRANVEWLDLGVVSDDPE
AIRHAFRHAASQADMVLTSGGVSVGEADFTKQILDEEGKITFWKLAIKPGKPFAMGRIGK
AIFCGLPGNPVSSMVTFYKLVWPILNKMQGLTPKAPLMLSATLTTPVRKQPGRVEYQRGI
LSRNAQGELEVAITGSQGSGMLTSMSLANCFVQLEQFQGDTPAGSQVTVEPFNSVLC