Protein Info for SO0054 in Shewanella oneidensis MR-1

Annotation: conserved hypothetical protein TIGR00275 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03486: HI0933_like" amino acids 6 to 394 (389 residues), 325.4 bits, see alignment E=9.2e-101 PF07992: Pyr_redox_2" amino acids 6 to 166 (161 residues), 32.4 bits, see alignment E=2.7e-11 PF00890: FAD_binding_2" amino acids 7 to 51 (45 residues), 36.1 bits, see alignment 1.8e-12 TIGR00275: flavoprotein, HI0933 family" amino acids 8 to 394 (387 residues), 432.9 bits, see alignment E=5.3e-134 PF13450: NAD_binding_8" amino acids 10 to 41 (32 residues), 23.7 bits, see alignment (E = 1.9e-08) PF22780: HI0933_like_1st" amino acids 191 to 341 (151 residues), 164.8 bits, see alignment E=6.3e-52

Best Hits

KEGG orthology group: K07007, (no description) (inferred from 100% identity to son:SO_0054)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EKN8 at UniProt or InterPro

Protein Sequence (396 amino acids)

>SO0054 conserved hypothetical protein TIGR00275 (NCBI ptt file) (Shewanella oneidensis MR-1)
MSVKHHDVIIIGAGAAGLMCAATAGYRGRDVLVLDNAKQAGRKILISGGGRCNFTNLKVE
PANFICGNPHFVKSALARYPSQQFIELVERHGIEYHERDHGQLFCNDSAKEIVTMLLTEC
EWAGVSIKLRTDILSVGKNEAGRFELNTSNGELSCDSLVIATGGLSMPKLGATPYGYQLA
EQFGLKVLPTHAGLVPFTWHSEDKIRFEPLSGIAVPSRITAKDGTAFSEALLFTHRGLSG
PAILQISNYWKAGETIKINLLPNMDAAQAIEQQLAAHPKQSLRNTLSLWLPKRLVEVLFD
EVLLNKALNQLVHAERAKLVDDLHRWTVLMNGTEGYRTAEVTLGGVDTHELSSKTMEAIK
VPGLFFIGEVMDVSGWLGGFNFQWAWASGVAAGKAV