Protein Info for SO0045 in Shewanella oneidensis MR-1
Annotation: Rrf2 family protein (NCBI ptt file)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 51% identical to NSRR_PHOPR: HTH-type transcriptional repressor NsrR (nsrR) from Photobacterium profundum (strain SS9)
KEGG orthology group: K13771, Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor (inferred from 100% identity to son:SO_0045)Predicted SEED Role
"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q8EKP6 at UniProt or InterPro
Protein Sequence (151 amino acids)
>SO0045 Rrf2 family protein (NCBI ptt file) (Shewanella oneidensis MR-1) MQLTRYTDFGVRTLMYLAVQPDRTTLFRISEITEVFDLSPNHVSKIVHHLGKLGYLETIR GKMGGFRLGKPAGEINLGQLIRSLENSLAPIDCSKPYCRFTPACQLKGVLAQAVEAYLNV LDQYSLLDIVSNRNELLALLPDMSISVLQLD