Protein Info for Rru_A3706 in Rhodospirillum rubrum S1H

Annotation: Aminotransferase, class I and II (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00155: Aminotran_1_2
  • amino acids 91 to 454 (364 residues), 130.9 bits, E=3.4e-42

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3706)

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate aminotransferase alternative (EC 2.6.1.17)" in subsystem Lysine Biosynthesis DAP Pathway (EC 2.6.1.17)

MetaCyc Pathways

• aspartate superpathway (23/25 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
• L-lysine biosynthesis I (9/9 steps found)

KEGG Metabolic Maps

• Lysine biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.17

Use Curated BLAST to search for 2.6.1.17

Sequence Analysis Tools

See Q2RMZ5 at UniProt or InterPro

Protein Sequence (460 amino acids)

>Rru_A3706 Aminotransferase, class I and II (NCBI) (Rhodospirillum rubrum S1H)
MAFAAGFVQGVRPFWPKGSPTDGTGACPFPGGRVLFRPHPPGRARPLFGVSRPRSVADHP
MINPRLIALPDYPFQRLATLLAGVAPGADPLALSVGEPQHPTPALAGLELARHGDQWRRY
PPAAGNERWKAAVTAWLTRRYGLPAAMIDPHAVIPASGTREALYMLGQVLTDGRGEAGER
PLVVMPDPLYLPYLGAARMNGATILAVPGSEEGDFLPDIAGLPAATLERAAAVFVCSPAN
PQGSIVSLESWKTLVGLARRHGFVLVADECYSEIYDDQPPPGVLEACRDLGGSLKNVLVL
NSLSKRSNGAGLRSGLIAGDRALIDAFLRLRAYASAGMPLPIMEASAALWDDETHVEANR
ALYREKIDLAAARLKGMLGFRRPPGGFFLWLDTTPWGETGEQATLRLWRDHGLKVLPGAY
MTANPDAGDNPARNRLRLALVHDGPVVARALDRLVAASPH