Protein Info for Rru_A3580 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF6, transmembrane (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 23 to 23 (1 residues), see Phobius details amino acids 33 to 53 (21 residues), see Phobius details amino acids 65 to 85 (21 residues), see Phobius details amino acids 95 to 113 (19 residues), see Phobius details amino acids 120 to 144 (25 residues), see Phobius details amino acids 150 to 169 (20 residues), see Phobius details amino acids 181 to 199 (19 residues), see Phobius details amino acids 211 to 229 (19 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 265 to 283 (19 residues), see Phobius details PF00892: EamA" amino acids 8 to 137 (130 residues), 69 bits, see alignment E=2.7e-23 amino acids 151 to 281 (131 residues), 39.8 bits, see alignment E=2.8e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3580)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNC1 at UniProt or InterPro

Protein Sequence (294 amino acids)

>Rru_A3580 Protein of unknown function DUF6, transmembrane (NCBI) (Rhodospirillum rubrum S1H)
MSSSRATLIGSTAVLMWGTLALLTTWTGAVPPFQLTAMSFTIAFLLMAAKWLSRGERPAA
HLRQPVAAWILGVFGLFGYHFFYFMALREAPPVEAGLIAYLWPLLIVLFSALLPGERLRW
FHVAGALMGLAGTVLLVTRGGAIAFDPTHLVGHLAALVCAVTWATYSVLSRRFGTVPTDA
VGWFCGATALLALPCHLIFETTHWPEGAGQWLAVLALGLGPVGAAFFTWDHGVKHGDIQV
LGALSYGAPLISTALLIAFGKGEATALVGAACLLIVGGALLAGKSMLARSKRGG