Protein Info for Rru_A3576 in Rhodospirillum rubrum S1H

Annotation: UDP-glucuronate 5'-epimerase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF04321: RmlD_sub_bind" amino acids 1 to 211 (211 residues), 65.4 bits, see alignment E=1.4e-21 PF01073: 3Beta_HSD" amino acids 4 to 235 (232 residues), 73.2 bits, see alignment E=5.8e-24 PF16363: GDP_Man_Dehyd" amino acids 4 to 324 (321 residues), 166.5 bits, see alignment E=3.5e-52 PF02719: Polysacc_synt_2" amino acids 4 to 233 (230 residues), 43.6 bits, see alignment E=6.9e-15 PF01370: Epimerase" amino acids 4 to 234 (231 residues), 191.6 bits, see alignment E=4.7e-60 PF07993: NAD_binding_4" amino acids 74 to 184 (111 residues), 25.1 bits, see alignment E=2.8e-09

Best Hits

Swiss-Prot: 50% identical to CAPI_STAAU: Protein CapI (capI) from Staphylococcus aureus

KEGG orthology group: K01789, UDP-glucuronate 5'-epimerase [EC: 5.1.3.12] (inferred from 100% identity to rru:Rru_A3576)

Predicted SEED Role

"Nucleotide sugar epimerase"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNC5 at UniProt or InterPro

Protein Sequence (335 amino acids)

>Rru_A3576 UDP-glucuronate 5'-epimerase (NCBI) (Rhodospirillum rubrum S1H)
MTTLVTGTAGFIGSHVALRLLQEGEQVVGIDCYTPYYDVGLKEARVARLKAFPGFSEHRL
DLADEAGVDAVFRAARPRRVIHLAAQAGVRYSVENPRAYLESNLMGTFSVLEGCRKTGVE
HLVFASTSSVYGANKTQPFSEHQPADHPLTFYAATKRATEMMAHSYANIYQLPSTALRFF
TVYGPWGRPDMALFLFTEAMLKGEPIRVFNHGKMVRDFTYIDDIVDGILRASAKIPVAMA
GGAAQPDPAGSPVGPFRVYNIGNSQPVELMRYIEVLEGCLGVTAKKEMLPMQLGDVPGTW
ADVSALAADTGYAPKIGVEEGVRRFVDWYRGYYKP