Protein Info for Rru_A3443 in Rhodospirillum rubrum S1H

Annotation: PAS/PAC Sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 801 transmembrane" amino acids 15 to 36 (22 residues), see Phobius details PF12860: PAS_7" amino acids 321 to 434 (114 residues), 29 bits, see alignment E=2.5e-10 amino acids 450 to 561 (112 residues), 30.5 bits, see alignment E=8.8e-11 PF00512: HisKA" amino acids 576 to 644 (69 residues), 61.2 bits, see alignment E=2e-20 PF02518: HATPase_c" amino acids 691 to 799 (109 residues), 81.1 bits, see alignment E=2.1e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3443)

Predicted SEED Role

"FIG056333: sensor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNQ8 at UniProt or InterPro

Protein Sequence (801 amino acids)

>Rru_A3443 PAS/PAC Sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MFSDPSFADSVLPTQIGTLIVLVAGTVAVLMGGLALRWRSAWLRSLESRHQAEYEAEALR
EILATASDGYYLWALDGPLRGREFCSRRLAVLLRLPSGVNAELKEIIGVFAEGDAQALEG
MIAVLRREGRGFVLDLLLAASGRRVRTVGIRANAGDGHALADLLWMRDVTEETRVGDVQG
RRAQALQAERDRLRAVVDALPAPIWTRDDSLAIGDGNTALARALDLGSAGDALTARRELA
PGATGQEMRALAARSRAAGRPARARFHAVLDGERKLLEITETPLSEGPLRGHTVGIAQDI
TPIEEVESRLERETEAHAEVLERLGSAIAIFGGDTRLSFHNAAFASLWGLESDWLNGEPS
YGDFLERQRENRRLPEVADFPAYKAGELGYFTKLLRPREDILHLPDGATLRRVIAPHPLG
GLITTFEDVTDSLALERSYNQLTAVQRETIDHLHEAVAVFGANGRLRLSNPAFSQLWSGA
GTDSEPQAAALLDDMEAAMIADGAWETFRRRLCVRDESAGPRNGRLVRRDGRHLDYATVP
LPDGGLLLSILDITDRVRVEQALSERTEALRAADMMKSEFIANVSYELRTPLTTISGFSE
ILSGAYYGELNTRQREYAEVITETSRQVVRLIDEITDLVSMQAGKLALELDAFDIHAALA
AVLALGRESARRRGVTLNFDCPPDAGWMVADETRIKQILFHLMSNAITGTDAGGQVTLAV
QREDTPDGGTMVFTVADTGRGMDEILQTRAFESFAKGPRADGAGLGLALVRRFVELHGGA
VDLVSVPGEGTTVTVRIPTSG