Protein Info for Rru_A3402 in Rhodospirillum rubrum S1H

Annotation: sulfate ABC transporter, permease protein CysW (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 transmembrane" amino acids 31 to 54 (24 residues), see Phobius details amino acids 76 to 101 (26 residues), see Phobius details amino acids 112 to 138 (27 residues), see Phobius details amino acids 151 to 172 (22 residues), see Phobius details amino acids 212 to 236 (25 residues), see Phobius details amino acids 257 to 278 (22 residues), see Phobius details TIGR02140: sulfate ABC transporter, permease protein CysW" amino acids 29 to 287 (259 residues), 417.4 bits, see alignment E=2.4e-129 TIGR00969: sulfate ABC transporter, permease protein" amino acids 33 to 285 (253 residues), 330.9 bits, see alignment E=6.4e-103 PF00528: BPD_transp_1" amino acids 92 to 285 (194 residues), 43.7 bits, see alignment E=1.3e-15

Best Hits

Swiss-Prot: 57% identical to CYSW_SYNY3: Sulfate transport system permease protein CysW (cysW) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02047, sulfate transport system permease protein (inferred from 100% identity to rru:Rru_A3402)

MetaCyc: 52% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysW (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysW" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNU9 at UniProt or InterPro

Protein Sequence (297 amino acids)

>Rru_A3402 sulfate ABC transporter, permease protein CysW (NCBI) (Rhodospirillum rubrum S1H)
MAASPSSSAVLPTDRSVARAAVSERPVARGLLILAAVLFLCLFLLLPLVAVFVEALSDGV
ATYFRALTDPDAMSSIRLTLMVAAISVPLNLVFGVAAAWAVAKHDFPGRSLLVTLIDLPF
SVSPVISGLCYVLVFGAQGWFGPWLVDHGVRIVFAVPGIVLATVFVTLPFIARELIPLME
EQGSDDEEAALSLGATGWQTFMRVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRG
LTNTMPLHVEILYNEYSFAAAFAVASLLAVLALVTLVLKTALESRHGADLARGSGRH