Protein Info for Rru_A3401 in Rhodospirillum rubrum S1H

Annotation: sulfate ABC transporter, permease protein CysT (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 68 to 92 (25 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details amino acids 138 to 162 (25 residues), see Phobius details amino acids 194 to 212 (19 residues), see Phobius details amino acids 218 to 241 (24 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details TIGR02139: sulfate ABC transporter, permease protein CysT" amino acids 16 to 277 (262 residues), 417.9 bits, see alignment E=1.9e-129 TIGR00969: sulfate ABC transporter, permease protein" amino acids 18 to 274 (257 residues), 318.7 bits, see alignment E=3.3e-99 PF00528: BPD_transp_1" amino acids 81 to 280 (200 residues), 66.5 bits, see alignment E=1.4e-22

Best Hits

Swiss-Prot: 54% identical to CYST_SYNY3: Sulfate transport system permease protein CysT (cysT) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02046, sulfate transport system permease protein (inferred from 100% identity to rru:Rru_A3401)

MetaCyc: 51% identical to sulfate/thiosulfate ABC transporter inner membrane subunit CysU (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]; ABC-7-RXN [EC: 7.3.2.5, 7.3.2.3]; 7.3.2.3 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-478 [EC: 7.3.2.5, 7.3.2.3]; TRANS-RXN0-479 [EC: 7.3.2.5, 7.3.2.3]

Predicted SEED Role

"Sulfate transport system permease protein CysT" in subsystem Cysteine Biosynthesis

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.3 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNV0 at UniProt or InterPro

Protein Sequence (283 amino acids)

>Rru_A3401 sulfate ABC transporter, permease protein CysT (NCBI) (Rhodospirillum rubrum S1H)
MTRSIGPKLLGGPRAIPGFGMTLGFTLAYLGLLVLLPLAAVVIKAASLGPADFWAIATAP
RTLAALRLSFGAALLAAAINMVFGLLVAWVLVRYDFPGRRILDALVDLPFALPTAVAGIA
LTGLYANNGWIGQYLEPLGLKVAFAPAGVVVALTFVGLPFVVRTVQPVLADLEREAEEVA
ATLGAGRWDTFRRVLMPALAPALLTGFALSFARGVGEYGSVIFIAGNIPMVSEIAPLLIV
IKLEEFDYRGATAVAAVMLALSFALLLAINLLQSWSRARMTTR