Protein Info for Rru_A3371 in Rhodospirillum rubrum S1H

Annotation: Zinc-containing alcohol dehydrogenase superfamily (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 PF08240: ADH_N" amino acids 28 to 87 (60 residues), 41.6 bits, see alignment E=1.5e-14 PF00107: ADH_zinc_N" amino acids 151 to 270 (120 residues), 119.4 bits, see alignment E=1.5e-38 PF13602: ADH_zinc_N_2" amino acids 184 to 322 (139 residues), 77.3 bits, see alignment E=3.5e-25

Best Hits

Swiss-Prot: 40% identical to QORL2_NEMVE: Quinone oxidoreductase-like protein 2 homolog (v1g238856) from Nematostella vectensis

KEGG orthology group: K00344, NADPH2:quinone reductase [EC: 1.6.5.5] (inferred from 100% identity to rru:Rru_A3371)

Predicted SEED Role

"Quinone oxidoreductase (EC 1.6.5.5)" in subsystem ZZ gjo need homes (EC 1.6.5.5)

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.5

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNY0 at UniProt or InterPro

Protein Sequence (325 amino acids)

>Rru_A3371 Zinc-containing alcohol dehydrogenase superfamily (NCBI) (Rhodospirillum rubrum S1H)
MRAMVCDAFGPPDVLRVADLPDPPLPPDGVRIRVRAAGINFADGLFIAGQYQIRPRPPFI
PGFEVAGDILEVGPEVLDLRPGQRVMAILDQGGYADQVVAPARDVHALTDRMDLLAAGGF
PIAYGTSHFGLTDRCRLRPGEIVLIHGAAGGVGLTAVECAKALGATVIATAGGADRLEIA
RQHGADYGIDHRNENIKARVRELTGGRGVDVVYDPVGGDVFDASLRCTAPDGRILVVGFA
SGAIPTPPANLLLVKNITVIGFNWGGYRQIAEQRVRESMEDVVSWWDRGLVTPHVGARFA
LSQAAEALAALRERKIIGKAVLIPD