Protein Info for Rru_A3357 in Rhodospirillum rubrum S1H

Annotation: Transcriptional Regulator, AraC family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 486 PF02805: Ada_Zn_binding" amino acids 15 to 78 (64 residues), 102.3 bits, see alignment E=2.8e-33 PF12833: HTH_18" amino acids 113 to 191 (79 residues), 77 bits, see alignment E=2.9e-25 PF06029: AlkA_N" amino acids 205 to 319 (115 residues), 130.2 bits, see alignment E=1.2e-41 PF00730: HhH-GPD" amino acids 325 to 468 (144 residues), 38.7 bits, see alignment E=2.8e-13

Best Hits

KEGG orthology group: K13529, AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC: 3.2.2.21] (inferred from 100% identity to rru:Rru_A3357)

Predicted SEED Role

"ADA regulatory protein" in subsystem DNA repair, bacterial

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.2.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNZ4 at UniProt or InterPro

Protein Sequence (486 amino acids)

>Rru_A3357 Transcriptional Regulator, AraC family (NCBI) (Rhodospirillum rubrum S1H)
MTQHDPNPPSDPSLCHRAVAARDKRFDGRFFTCVRTTGIFCRPICPARTPAMENCLFVAT
AAQALAAGFRPCLRCRPEAAPGLGGWLGTAASVNRALALIGEGALDEGSVAALAERLGLG
ERHLRRLFLHHLGISPGAVAQAQRLLFAKTLISDTALPMTEIALAAGYGSLRRFNHALRT
AYGCPPTALRRAKGAAIVGEGGPVLRLAARQPFDWPGLLAFFRQRAVPGLERVEGDTYVR
AIAIGAARGVVTIRGSAEGLVVTPSLDRPEGLAALVARLRRVFDLDADIGAIGAHLGADP
LLAPLVAARPGLRVPGAWDGFELAVRAILGQQVSVAAATTLAGRLVGAFGEPLTNAPPAG
PSRLFPTAARLAEADLGGLGLTTARAKAISGLARAVVETPGLLDPGPDLDSAVARLCRLP
GIGPWTAQYIALRALGEADALPVGDIGVLRALAEDGVRPTPAALLARAEDWRPWRSYAVL
HLWSMP