Protein Info for Rru_A3335 in Rhodospirillum rubrum S1H

Annotation: Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 signal peptide" amino acids 1 to 48 (48 residues), see Phobius details transmembrane" amino acids 95 to 115 (21 residues), see Phobius details PF02518: HATPase_c" amino acids 237 to 340 (104 residues), 46.7 bits, see alignment E=2e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3335)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RP16 at UniProt or InterPro

Protein Sequence (346 amino acids)

>Rru_A3335 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MSGPTTSSVSSARPIADRSPSSLGFAIRLLALCAVLVALAQAPVLVAATAGRLGGTPLAP
PPSWAEIGRTALALTASGDAGEAARADLLDTARGILPLSLPLAAGTGVLVFLVLLRQGRA
PARRVLAFSAESPQSSPGAEGAVLDRALARIGHDLQAGLAGAVAAGETPPPAVVRAVEDA
LLLVASARRFAGAPAPSPRLARVRVADLLGRVVDHLAAAHPGVTWRLDTPESLVLKGDEA
HLFRILVSLGRNAAQVGSRSVALRAERGEGWVFLDVIDDGPGVDPLTRDSLFQAFAGPSR
PGAAGVGLAVARDLARAQGGDLALVDGTIEGATFRLSLPAAGKPSS