Protein Info for Rru_A3248 in Rhodospirillum rubrum S1H

Annotation: Chromosome segregation protein SMC (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1167 TIGR02168: chromosome segregation protein SMC" amino acids 4 to 1150 (1147 residues), 803.9 bits, see alignment E=1.3e-245 PF02463: SMC_N" amino acids 5 to 1143 (1139 residues), 194.6 bits, see alignment E=3.1e-61 PF13476: AAA_23" amino acids 6 to 229 (224 residues), 46.2 bits, see alignment E=1.8e-15 PF06470: SMC_hinge" amino acids 514 to 599 (86 residues), 23.6 bits, see alignment 1.2e-08

Best Hits

KEGG orthology group: K03529, chromosome segregation protein (inferred from 100% identity to rru:Rru_A3248)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPA2 at UniProt or InterPro

Protein Sequence (1167 amino acids)

>Rru_A3248 Chromosome segregation protein SMC (NCBI) (Rhodospirillum rubrum S1H)
MLHFTRLRLVGFKSFVEPAELMIEPGLTGVVGPNGCGKSNVVEALRWVMGETSAKQLRGE
DMDDVIFGGTASRPPRNVAEVTLLLDNREGGAPALFNAAQELEVTRRIARGDGSLYRVNG
KDVRARDVQLLFADSATGARSTAMVSQGRVSALIAAKPAQRRALLEEAAGIGGLYSRRHE
AELRLRAAEGNLERLEDVVTALDGQLGGLRRQSRQAARYRALSEAIRQTEAALLRQRWLV
AIRAVDGARRIFAEGGRELAVLSGRTITANREQAAAEEAIGPIRSHEAEASARLQRLALA
REQLEAESRRLAQTAQENHTRRTQAEADRARETARAADAQAAISRLEGERRAIEAKAAGD
DAARREAEARLSAAEAGVAEADAALATATATLADLEARRAAQERGLREAIARGAKVVARL
AELEGQIRAAEGEAIAPGALEEAIQTRDRTVAALEAARERVESGEAARTAAQAAVDLAQD
SLRRAEGRLTGLRAEARALEATLARAAPKGRTLPVVEALSVRPGGEKALASALGDDLDAG
SAEEDAVRWVALPALAADPPDATTPLADLVEGPEAVRALLARRLGRVGVVEDAAAAQALL
PRLTPGQEVVDRAGGLWRWDGLVRRPGSRDGAALSAARLETRNRLGALATEREDAEAALA
EARDAHGAARARLEAVAAEDRAAREAVRAGERQMGLARDALTTLERRAAASESRLTTLGQ
ALTRAREDGAEAEAVVAAQSRALAALDDSAAARAAVAELRATLAERRTTLLEARATRDRV
AREAEGRGRRLGALAAEITSWRARRDQAADQEAELTRRFAAAEATLAELVGRPEAIAAEK
AALVEALRAAESDRLAARDALSAAERRLSEAGRTLKEAERAEAQAREVQLRGEATLDQAR
LACQAAAAAIAEKFDCAPEALAGQAGLGADETLAPVAEAEAALLRLGREREAMGPVNLRA
EQEAGELDAQITSLRLERDDLVAAIARLRQGIGELNREGRSRLLESFQRVDGHFRTLFLK
LFGGGRAHLTLIESDDPLEAGLEIMASPPGKRLQSLGLLSGGEQALTATALLFAVFLTNP
APICVLDEVDAPLDDANVDRFCAMLRHLTDTTGTRFLVVTHHRMTMARMDRLFGVTMAER
GVSSLVSVDLCQAEDLVEAESPAAVLA