Protein Info for Rru_A3236 in Rhodospirillum rubrum S1H

Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 transmembrane" amino acids 272 to 295 (24 residues), see Phobius details amino acids 526 to 551 (26 residues), see Phobius details amino acids 580 to 603 (24 residues), see Phobius details amino acids 615 to 633 (19 residues), see Phobius details PF00005: ABC_tran" amino acids 28 to 176 (149 residues), 103.8 bits, see alignment E=1.8e-33 PF12704: MacB_PCD" amino acids 275 to 495 (221 residues), 161.6 bits, see alignment E=4.8e-51 PF02687: FtsX" amino acids 531 to 643 (113 residues), 69 bits, see alignment E=6e-23

Best Hits

Swiss-Prot: 100% identical to MACB_RHORT: Macrolide export ATP-binding/permease protein MacB (macB) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K05685, macrolide transport system ATP-binding/permease protein [EC: 3.6.3.-] (inferred from 100% identity to rru:Rru_A3236)

Predicted SEED Role

"Macrolide export ATP-binding/permease protein MacB (EC 3.6.3.-)" in subsystem Multidrug Resistance Efflux Pumps (EC 3.6.3.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPB4 at UniProt or InterPro

Protein Sequence (650 amino acids)

>Rru_A3236 hypothetical protein (NCBI) (Rhodospirillum rubrum S1H)
MADTPPPLIELIDLERVFDSSEVPVRALDRVSLTIHEGEFVAIIGQSGSGKSTLMSILGC
LDRPTGGLYRLGGIDVASLDPVALAGLRRDTFGFVFQRYNLLAGASAAENVEMPAVYAGQ
PRHQRLERAHALLDRLGMGARSGHFPNQLSGGQQQRVSIARALMNDPRVILADEPTGALD
SASGRDVLALLEALHTEGRTVILITHDRDVAARAERVIALQDGRVVEDSGRPAPVGSDRP
LGRPPGGAAYLGMAASFGEALKMAGRSLRANIFRTALTLLGVVIGVAAVVTMMAIGEGSK
QDVLTRIQSMGTNLLLVRPGAPGIRPSGTDVSLTPTDAEAVAQLAGMAAVAPERMASGIT
VRREGIDYRTTINGTWPAYAAAKDWPMAWGSFFDATDLQASAPVAVLGQTVAKNLFPGEE
DPVGSYFLVRNVPFLVIGVLEAKGATPFGQDQDDIVLIPLTTAFARVSGGRYLSSLTARV
EDATTIDESQAAIESLLQARHGKVDFQVRNTQSLLEMVEKTQNSLTLLLGAVALISLLVG
GIGVMNIMLVSVTERTREIGIRLATGARASDILLQFNTEAVAVCGVGGLAGVGLGLGAAL
AVAEFGLPVRFTPGPPIVAFCCAFLTGLLFGYLPARKAARLDPVVALSAE