Protein Info for Rru_A3233 in Rhodospirillum rubrum S1H

Annotation: Threonine synthase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF14821: Thr_synth_N
  • amino acids 2 to 80 (79 residues), 99.4 bits, E=1e-32
• TIGR00260: threonine synthase
  • amino acids 68 to 428 (361 residues), 282.7 bits, E=2e-88
• PF00291: PALP
  • amino acids 99 to 332 (234 residues), 72.8 bits, E=3.2e-24

Best Hits

KEGG orthology group: K01733, threonine synthase [EC: 4.2.3.1] (inferred from 100% identity to rru:Rru_A3233)

Predicted SEED Role

"Threonine synthase (EC 4.2.3.1)" in subsystem Threonine and Homoserine Biosynthesis (EC 4.2.3.1)

MetaCyc Pathways

• aspartate superpathway (23/25 steps found)
• superpathway of L-isoleucine biosynthesis I (13/13 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (16/18 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (13/15 steps found)
• superpathway of L-threonine biosynthesis (6/6 steps found)
• L-threonine biosynthesis (2/2 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism
• Vitamin B6 metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.3.1

Sequence Analysis Tools

See Q2RPB7 at UniProt or InterPro

Protein Sequence (470 amino acids)

>Rru_A3233 Threonine synthase (NCBI) (Rhodospirillum rubrum S1H)
MRYVSTRGQAPVLSFDDVLLAGLASDGGLYVPQTWPSFSEDDIRDMRALTYQELAVRVMG
PFMGAAVTDDELTEVVEQAYAGFSHPAVAPLVQIGAHDWVMELFHGPTLAFKDYALQVVG
GLFDLILTRRGSRITVVGATSGDTGSAAIEACRDREAVDVIILLPKGRVSEVQRRQMTTV
TSSNVHAIEVEGTFDDCQALVKALFNDPAFRSEVNLAAVNSINWARIMAQTVYYFWAALQ
LGAPDRSLGFSVPTGNFGNVLAGYCAKRMGLPIDRLVVGSNSNDILTRFLETGTMQSRGV
VQTHSPSMDIQVSSNFERLLFEVVDRDSAEVERLMAQFALTGGYTLDSALHQELLGLFRG
FRVDNDATLRAIAELYAATGMILDPHSVIGVIAGREAGHRDTGTPMVALATAHPAKFADV
VEQATGQRPALPGALSDLLTRPERRAEVANDPEAVKALVRSLSRVPGASA