Protein Info for Rru_A3203 in Rhodospirillum rubrum S1H

Annotation: ribonuclease R (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 842 TIGR02063: ribonuclease R" amino acids 57 to 766 (710 residues), 654.8 bits, see alignment E=1.7e-200 TIGR00358: VacB and RNase II family 3'-5' exoribonucleases" amino acids 173 to 755 (583 residues), 462 bits, see alignment E=3.2e-142 PF17876: CSD2" amino acids 217 to 288 (72 residues), 33.5 bits, see alignment E=5.7e-12 PF00773: RNB" amino acids 306 to 633 (328 residues), 316.6 bits, see alignment E=3e-98 PF00575: S1" amino acids 683 to 733 (51 residues), 24 bits, see alignment 6.1e-09

Best Hits

KEGG orthology group: K12573, ribonuclease R [EC: 3.1.-.-] (inferred from 100% identity to rru:Rru_A3203)

Predicted SEED Role

"3'-to-5' exoribonuclease RNase R" in subsystem RNA processing and degradation, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPE7 at UniProt or InterPro

Protein Sequence (842 amino acids)

>Rru_A3203 ribonuclease R (NCBI) (Rhodospirillum rubrum S1H)
MPSLAPLWHDGADPGNGIRARRVFPQDSLWLSRPNRRFPDPKDSPLTPKAPKHVPFPSRE
QVLEFIRAANGEVDRREIARAFHITGPERADLRTLLKELESEGALQRGRGRRIAPPGSLP
EVAVLIVARADAEGDLFCKPEHWPEDEEPPRILLWPEPHHARRPGVGAEIGVGDRILARL
TRIGDARYDARTIRRLAAAPSRLLGVLALARDGLRLRPTNRRDRDEYLVAPEDAGGAEPG
ELVEAELLPSRRLGLRRAKVIERLGGREGPRSISLVVVHSHDIPVDFPPEALAEAEAAVG
VDLRGREDLRAVPLVTIDGEDARDFDDAVFAEPDDDPANPGGWRALVAIADVAHYVRIGA
ALDKAARERGNSVYFPDRVVPMLPEALSNGWCSLRPNEDRGCLAVWMIFDAEGNKLRHRF
LRGLMRSAARLTYTQVQAARDGHADDLTAPLQERVIAPLYGVFQALLGARSRRGTLELDL
PERKVVLDDGGEVARIEPRLRFDSHKLIEELMIAANVSAAETLEEKRRPCMYRVHDQPAP
DKLVALGEFLESLDIPFHKGSINRSGQFNGVLKAARGTPHEHMVNEVVLRSQAQAEYSPD
NIGHFGLALRRYAHFTSPIRRYADLLVHRALIAGLGLGDDGLRPGAEEDFVETAAHITAT
ERRAAQAERDAVNRYTVSFLAAKVGATFAGRINGVTRAGLFVTLEDTGADGLIPIGSLPN
DYYVHDDAHHCLRGQRDGLEFHLGAPVEVLLREANPVSGGLVFGLLQGGVAGAAKGRGFS
GKTKGRDGLGKTRLKERGAAAKLKKGARGKPKAAGRDALAGEPVGSGPKKRPPTTTSRRK
TR