Protein Info for Rru_A3058 in Rhodospirillum rubrum S1H

Annotation: putative suppressor for copper-sensitivity B precursor (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 715 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 310 to 335 (26 residues), see Phobius details amino acids 355 to 376 (22 residues), see Phobius details amino acids 396 to 416 (21 residues), see Phobius details amino acids 438 to 466 (29 residues), see Phobius details amino acids 473 to 493 (21 residues), see Phobius details amino acids 513 to 530 (18 residues), see Phobius details amino acids 536 to 555 (20 residues), see Phobius details amino acids 564 to 584 (21 residues), see Phobius details PF11412: DsbD_N" amino acids 45 to 156 (112 residues), 70.6 bits, see alignment E=1.3e-23 PF13899: Thioredoxin_7" amino acids 600 to 686 (87 residues), 56.3 bits, see alignment E=2.9e-19

Best Hits

KEGG orthology group: K08344, suppressor for copper-sensitivity B (inferred from 100% identity to rru:Rru_A3058)

Predicted SEED Role

"Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange (EC 1.8.1.8)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPU2 at UniProt or InterPro

Protein Sequence (715 amino acids)

>Rru_A3058 putative suppressor for copper-sensitivity B precursor (NCBI) (Rhodospirillum rubrum S1H)
MSRFLLALCLFLGLCLPAQAQGNDPGASAWVEKSHSRMRLISAVSAAGKAEEIALGLQVE
LAPHWKIYWRSPGDAGYPPSFDWTGSLNLAGATPRWPVPTRFSVLGIETVGYEHQVILPL
MARLERPGDPLILRLAVDYLICAEVCVPDRGDFTLIVPPGPSGASPQAQALARFLAQVPG
PSPSHGITVDEAVIETGGVVRVAVRADPPLAAPDLFVEAPAGMAFARPQVTVEEGGGRAV
LRAGVVGGDALIGQSLPVLVADGVRGVEAGVDTRRALAPPAGAGDPRPTALGGESGGETG
APGAPTGPLAFLAMVSVALLGGLILNLMPCVLPVLSLKILGLVGHGGGAPRAARLSFLAT
SAGIIASFLVLALAAIGLKTAGMAVGWGIQFQQPLFLSGMVVLLALFAANLWGLFEIGLP
GAVSGLGGQGRAGSSLSGAFATGAFATVLATPCSAPFLGTAVGFALARGPFEILAIFLAL
GLGMALPYLLVALRPQIATRLPRPGRWMLRLKAVLGAVLCLTALWLLSVLAVQIGAVWAA
VIGGLLAVALGVRALRPISRLSGGVAALLGIAALALPALPLPALSLPMAAPSQALEETAW
GRWSPEAVARLVAEGKTVLVDVTAQWCVTCKVNKATVLDAAPTRALLDSGRLSGLRADWT
RPDPAIAAYLASFGRFGIPFNAVYGPGAPQGIALPELLSENALLEAVARAAGPSS