Protein Info for Rru_A2986 in Rhodospirillum rubrum S1H

Annotation: Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 432 to 458 (27 residues), see Phobius details TIGR02485: precorrin 3B synthase CobZ" amino acids 21 to 475 (455 residues), 490.2 bits, see alignment E=2.7e-151 PF12831: FAD_oxidored" amino acids 22 to 53 (32 residues), 30.7 bits, see alignment (E = 3.3e-11) PF00890: FAD_binding_2" amino acids 22 to 453 (432 residues), 96 bits, see alignment E=4.5e-31 PF13450: NAD_binding_8" amino acids 25 to 77 (53 residues), 25.5 bits, see alignment 2e-09

Best Hits

KEGG orthology group: K13796, tricarballylate dehydrogenase (inferred from 100% identity to rru:Rru_A2986)

Predicted SEED Role

"TcuA: flavoprotein used to oxidize tricarballylate to cis-aconitate" in subsystem Tricarballylate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ14 at UniProt or InterPro

Protein Sequence (477 amino acids)

>Rru_A2986 Fumarate reductase/succinate dehydrogenase flavoprotein-like (NCBI) (Rhodospirillum rubrum S1H)
MIGPMPRIPPPSTPPEPAPACDVLVIGGGMAALCAAIAARRAGVSVRLVDAAPKALRGGN
SRHSRNFRLAHDTPTPLVPGRYPLAEFREDLITASGGLADPALIEILCAGSSTLPDWLAA
QGVDFQAPAEGALPWSRKTVFLRGGGKAMVNALYATCHRLGVVVENGWRASAVALADGPQ
TIALTGPGGALALCPAKTVILGSGGYQGDRLWLAETWGDQAAHFHNRGSPLVDGALLKAL
FAAGAARAGVAGACHLVAVDARSPREDGGIVTRVDGMPWGIVVDDSGRRFADEGAVIGPP
RYSTWGRLVAGRPRALAHVILDSAGLARSPASIYPPISAMTPAALAEKLALPVAPFVDTL
LAYNRAISGTGDGTGDDAHTLGLIPAKSRLARPLNAPPFHAYPMRPGTTFTGEGVGVDGE
ARVRRGENGPCLGLFAAGMIMAPALLGAGYLSGAALTIGGVFGRLAGEGAARRVRSL