Protein Info for Rru_A2930 in Rhodospirillum rubrum S1H

Annotation: Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 transmembrane" amino acids 15 to 40 (26 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details PF00672: HAMP" amino acids 79 to 131 (53 residues), 36.8 bits, see alignment 6.1e-13 PF00512: HisKA" amino acids 141 to 196 (56 residues), 32 bits, see alignment E=1.6e-11 PF02518: HATPase_c" amino acids 246 to 351 (106 residues), 92.7 bits, see alignment E=3e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2930)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ68 at UniProt or InterPro

Protein Sequence (352 amino acids)

>Rru_A2930 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MASGKKTSGLRRQIFLSMTVMAFSVVLLSICGSYVFYAVFLTYSPSSISDDLLPAPAEVA
WMTVTMLAALLLAAVIAIRLARRILTPLNSVADSLHRMAEGDLSARAVADDLSMGEATRL
VADFNNMAERLDGMARERAFWNAAIAHELRTPVTVLRGRLQGLAEGVFEPTPAMFSGLLI
HMEGLSRLVEDLRVLGLDESGRLELRLEQCDLAAEIAALINAFEPNLRAAGFVLAQDLDG
GEVVCDPMRIRQALSALLDNAIHHAEPGALQVRLRLEDERIRLQVEDKGPGIPTDLMECV
FDAFRRGAKPRLGGGSGLGLAVVRAIARAHGGEAACRASDSQGTIFELTWPA