Protein Info for Rru_A2925 in Rhodospirillum rubrum S1H

Annotation: Major facilitator superfamily MFS_1 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 30 to 56 (27 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details amino acids 94 to 116 (23 residues), see Phobius details amino acids 137 to 138 (2 residues), see Phobius details amino acids 140 to 143 (4 residues), see Phobius details amino acids 178 to 181 (4 residues), see Phobius details amino acids 186 to 207 (22 residues), see Phobius details amino acids 242 to 264 (23 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 304 to 327 (24 residues), see Phobius details amino acids 331 to 356 (26 residues), see Phobius details amino acids 367 to 388 (22 residues), see Phobius details amino acids 394 to 417 (24 residues), see Phobius details PF05977: MFS_3" amino acids 30 to 410 (381 residues), 55 bits, see alignment E=5.4e-19 PF07690: MFS_1" amino acids 34 to 300 (267 residues), 79.7 bits, see alignment E=2e-26 amino acids 258 to 411 (154 residues), 44.4 bits, see alignment E=1.1e-15

Best Hits

KEGG orthology group: K08217, MFS transporter, DHA3 family, macrolide efflux protein (inferred from 100% identity to rru:Rru_A2925)

Predicted SEED Role

"FIG00961795: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ73 at UniProt or InterPro

Protein Sequence (425 amino acids)

>Rru_A2925 Major facilitator superfamily MFS_1 (NCBI) (Rhodospirillum rubrum S1H)
MNADQAPAPLEKDSVIMMSDPGEGRWRLRFWTIFGGQVLSLCGSSLTQFVLMWWIADTTG
SVAALSVAGLAALLPHALFSPLGGVLADRYSRRVLMALTDIVSALCMVVLIALFLTERVE
MWHVYLMMAIRGAMQALQEPAAVASLGMLVPRSFLSRVGGLQQTLQSMTQVVAAPLGALA
MSVLPLGWALSIDVVTALFGIVPLLIFRIPQNQIPAGERTGVWREFRDGIGLVRRSRGLR
HLFLLLAVGLLAVMPSLMLVPLLVKEHFGGGAGEVALMEGLSGFGMIAGGMIVTAFAPRR
QVPWVLWGMSLSCLTLALTGLAPAGLFGVAVLWWVLSGLTYSLSAAPCMTLLQMVVPNHL
LGRTQSLLNTMLSLAAPVGLVITALLSAQVDVRALFVMTGAFAAIVTALGFLSPALMTLE
DTPPR