Protein Info for Rru_A2900 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF6, transmembrane (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 46 to 67 (22 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 137 to 160 (24 residues), see Phobius details amino acids 166 to 182 (17 residues), see Phobius details amino acids 194 to 212 (19 residues), see Phobius details amino acids 224 to 245 (22 residues), see Phobius details amino acids 257 to 276 (20 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details PF00892: EamA" amino acids 14 to 148 (135 residues), 84.3 bits, see alignment E=4.9e-28 amino acids 163 to 299 (137 residues), 82.5 bits, see alignment E=1.8e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2900)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ98 at UniProt or InterPro

Protein Sequence (308 amino acids)

>Rru_A2900 Protein of unknown function DUF6, transmembrane (NCBI) (Rhodospirillum rubrum S1H)
MASMPSLRDRVFSAYGLLILPQFLWATNAIVGKIAAQHAIPPVALAFWRWVLAFAFLLPF
AWSALVADRAKLRAHWPMVLVLGALSAGAYNALMYAALATSTAINVTLVASAMPVVMALL
ARVWLGERLNGRQGLGIVISALGVVVVVARGDITVLLSLALNRGDLLMLLAMASWSVYSV
LLRRHPLGLKPVSLLAGQIGAGVLVLVPIYAWERAGGAVLPLDLTTAWVLPYTAIFPAIF
AFYFWNRGVAAVGPSIAGVYTNLMPILTALLAVWLLGEEFAWYHMAGLALILGGIAFVTG
LPRRRAGA