Protein Info for Rru_A2668 in Rhodospirillum rubrum S1H

Annotation: SecY protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 79 to 102 (24 residues), see Phobius details amino acids 123 to 143 (21 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 191 to 211 (21 residues), see Phobius details amino acids 220 to 242 (23 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 320 to 342 (23 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 403 to 422 (20 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 24 to 432 (409 residues), 425.4 bits, see alignment E=1.2e-131 PF00344: SecY" amino acids 80 to 421 (342 residues), 390 bits, see alignment E=4.3e-121

Best Hits

Swiss-Prot: 58% identical to SECY_RICCN: Protein translocase subunit SecY (secY) from Rickettsia conorii (strain ATCC VR-613 / Malish 7)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 100% identity to rru:Rru_A2668)

MetaCyc: 56% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQY0 at UniProt or InterPro

Protein Sequence (447 amino acids)

>Rru_A2668 SecY protein (NCBI) (Rhodospirillum rubrum S1H)
MASAAEQLASNMNFGVFAKATELKKRIWFTLAALVVYRVGTYIPLPGIDPQAMADVFSRN
GGGILGMFDMFAGGALSRMTIFALNIMPYISASIIMQLMTSISPQLEALKKEGESGRKRI
NQYTRYLTVLITALQAYGIAVGLESMTSSSGAAVHDAGMFFRFTTVVTLMGGTLFLMWLG
EQITARGVGNGISLIIFTGIVAQLPHALVGMLELGRTGALSPAVILGILVLAVGVIAFIV
FMERAQRRILIQYPKRQQGNKMYGGESSHMPLKINTPGVIPPIFASSILLLPMTAAQFSA
GQGPEWLTTITTLLGHGQPLYMALYAALIAFFAFFYTAVVFNPEDTAENLKKYGGFIPGI
RPGRNTSEYLDYVLTRLTAVGAIYLIFISILPEFLISKVGVPFYFGGTSLLIVVTVTMDT
VAQIQSHLLAHQYEGLIKKSKLRGKRG